Select the statement which is not correct with respect to the factors affecting enzyme activity

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Select the statement which is not correct with respect to the factors affecting enzyme activity

1. Enzymes generally function at a wide range of temperature2. Every enzyme has an optimum pH at which it is most effective3. Increase in substrate concentration, increases the velocity of enzyme catalysed reaction at first.4. The temperature at which enzyme shows its highest activity is called its optimum temperature

Select the statement which is not correct with respect to the factors affecting enzyme activity